Plain language summaries of our case studies
We have been testing preference elicitation methods in clinical case studies. We have involved both patient partners and clinical research partners in the PREFER project case studies on lung cancer, rheumatoid arthritis and neuromuscular disorders. PhD students working in the project and partners from the pharmaceutical industry have also conducted their own case studies. Here we share some of our findings in plain language.
Preventing RA - What treatments do people at risk of rheumatoid arthritis prefer?
Rheumatoid arthritis, often referred to as RA, is a long-term condition that mainly affects the joints. RA causes pain, swelling, stiffness and often fatigue. If patients are not treated, their joints can suffer permanent damage, which can lead to disability. Preventative treatment can help. In this study, 350 first degree relatives of RA patients and 3000 members of the general public were asked to imagine that they had a 60% risk of developing RA in the next 2 years before being asked to make treatment choices. We have produced a plain language summary to describe the results from our case study that is now available for download.
Simons, G et al. Preventing RA: What treatments do people at risk of rheumatoid
arthritis prefer?. Zenodo. 2021. DOI: 10.5281/zenodo.5607650
Treating heart attacks with blood thinners - What do patients PREFER?
A myocardial infarction, or what is commonly known as a ‘heart attack’, happens when the large blood vessels that support the heart (known as the coronary arteries) are blocked and a part of the heart is deprived of oxygen. The blockage of your arteries is caused by a buildup of blood fats (cholesterol) and other substances in the artery walls. Without oxygen, muscle cells in the heart begin to die, which means you need to have medical treatment as soon as possible.
In this study, we asked more than 300 patients about their preferences- approximately half in the acute stage and half in the chronic stage of their disease. Most of them were men, on average, 64 years old. Many of the patients also had other medical conditions, like high cholesterol, high blood pressure, or diabetes, and several of them had already used medicines that thin the blood. All patients had been hospitalized after a heart-attack, they were over 18 and living in England. We asked them about their preferences when it comes to heart attack medications. Hoping to find how much value a person gives different risks and benefits of a particular treatment, and how they balance between them.
Pinto, CA & Tervonen, T. Treating heart attacks with blood thinners: What do patients PREFER?, Zenodo. 2022. DOI: 10.5281/zenodo.5840266